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Factors Associated with Seizure Onset in Children with Autism Spectrum Disorde

TitleFactors Associated with Seizure Onset in Children with Autism Spectrum Disorde
Publication TypeJournal Article
Year of Publication2020
AuthorsCapal, JK, Macklin, EA, Lu, F, Barnes, G
JournalPediatrics Supplement

Aims and Objectives:
Children with autism are more likely to have epilepsy than other children. This study aimed to identify risk factors for developing a seizure disorder/epilepsy over time.

Method: Participants included 472 children with autism who did not have a diagnosed seizure disorder. They were between the ages of 2 to 17 years. The researchers studied these children’s behavioral health, cognition, and quality of life at the beginning of the study and some at a later date. There was usually a gap of about four years between the two visits.

22 (4.7%) of the 472 children evaluated developed epilepsy after study enrollment. Compared to the other children, these 22 children were found to have worse social skills, quality of life and were more hyperactive at the beginning of the study. Their quality of life, social skills, and irritability level were even worse at the second visit. Increased difficulty with social skills were found to be a risk factor for developing seizures.

This study indicates that lower social skills in children with autism may affect future seizure disorders.