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Development of a Brief Parent-Report Screen for Common Gastrointestinal Disorders in Autism Spectrum Disorder.

TitleDevelopment of a Brief Parent-Report Screen for Common Gastrointestinal Disorders in Autism Spectrum Disorder.
Publication TypeJournal Article
Year of Publication2019
AuthorsMargolis, KG, Buie, TM, J Turner, B, Silberman, AE, Feldman, JF, Murray, KF, McSwiggan-Hardin, M, Levy, J, Bauman, ML, Veenstra-VanderWeele, J, Whitaker, AH, Winter, HS
JournalJ Autism Dev Disord
Volume49
Issue1
Pagination349-362
Date Published2019 Jan
ISSN1573-3432
KeywordsAutism Spectrum Disorder, Child, Female, Gastrointestinal Diseases, Health Surveys, Humans, Male, Parents
Abstract

Gastrointestinal dysfunction in children with autism spectrum disorder (ASD) is common and associated with problem behaviors. This study describes the development of a brief, parent-report screen that relies minimally upon the child's ability to report or localize pain for identifying children with ASD at risk for one of three common gastrointestinal disorders (functional constipation, functional diarrhea, and gastroesophageal reflux disease). In a clinical sample of children with ASD, this 17-item screen identified children having one or more of these disorders with a sensitivity of 84%, specificity of 43%, and a positive predictive value of 67%. If found to be valid in an independent sample of children with ASD, the screen will be useful in both clinical practice and research.

DOI10.1007/s10803-018-3767-7
Alternate JournalJ Autism Dev Disord
PubMed ID30350113
Grant ListK08 DK093786-01A1 / / National Institute of Diabetes and Digestive and Kidney Diseases /
4RO1NS015547 / / National Institute of Health /
PR160365 / / Department of Defense /
UA3 MC11054 / / Autism Speaks and cooperative agreement /
UA3 MC11054 / / Autism Speaks / United States
R01 NS015547 / NS / NINDS NIH HHS / United States
K08 DK093786 / DK / NIDDK NIH HHS / United States